The stories and people behind the humanitarian force that is UCSF
Charles CraikIn 1990, pharmaceutical chemist Charles Craik, PhD, discovered an inhibitor to HIV protease. The discovery validated the protease as a drug target and set the stage for creation of the class of drugs now known as protease inhibitors. Protease inhibitors are credited with a large reduction in the death rate among those infected with HIV, and have also been used to understand and combat other diseases, including malaria and Chagas’ disease.
